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Updated: Jan 9, 2026

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Quantitative Autonomic Testing
Published on: July 19, 2011
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长期COVID自主功能障碍的关联:使用定量自主测试进行评估
Ciana Keller1, Lorraine Mascarenhas2, Jorge L Reyes3
1Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, USA.
Journal of the American College of Cardiology
|December 10, 2025
概括
长期COVID患者表现出显著的自主功能障碍,与纯自主性衰竭患者相比. 这种持续的功能障碍在初始感染后很长时间就会影响心率和血压调节.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 传染性疾病 传染性疾病
背景情况:
- 长期COVID综合征,以COVID-19感染后的持续症状为特征,被怀疑涉及自主功能障碍.
- 长期COVID中自主性障碍的确切性质和严重程度尚不清楚.
研究的目的:
- 为了比较长期COVID患者的自主功能,健康的对照和已确定的纯自主衰竭的个体.
- 为了阐明长期COVID患者自主功能障碍的程度.
主要方法:
- 在三个组中进行了自主功能测试:长期COVID,COVID-19负控和纯自主功能衰竭患者.
- 测量包括活跃站立时的心率和血压反应,瓦萨尔瓦机动,呼吸道鼻节律失常和倾斜桌面测试.
主要成果:
- 与对照组相比,长期COVID患者在活动站立和倾斜桌面测试期间表现出更大的心率增加和血压下降.
- 与对照组相比,长期COVID患者的Valsalva比率和呼吸道鼻失常值有所降低.
- 经过年龄和性别调整后,长期COVID患者的自主功能障碍与纯自主性衰竭患者的功能障碍相似,感染后持续40个月.
结论:
- 长期COVID患者表现出持续的自主功能障碍.
- 这种功能障碍的严重程度类似于根据年龄和性别调整后,在纯自主性衰竭患者中观察到的情况.
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