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Updated: Jan 9, 2026

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis
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集群蛋白驱动介质细胞的纤维内细胞分裂,以解决肝纤维化

Minjun Wang1, Fei Chen2, Junling Gao2

  • 1Department of Cell Biology, Center for Stem Cell and Medicine, Naval Medical University, Shanghai, China; National Key Laboratory of Immunity and Inflammation, Naval Medical University, Shanghai, China.

Gastroenterology
|December 10, 2025
PubMed
概括

由衰老的肝细胞分泌的集群蛋白 (CLU) 通过促进纤维组织中皮细胞清除来逆转肝纤维化. 一种工程化,CLUtide,显示出治疗肝纤维化治疗的前途.

关键词:
原蛋白的清除 清除肝硬化是肝硬化的一种疾病.类介导疗法是一种类介导疗法.通过受体介导的内细胞分裂.空间转录组学 空间转录组学

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