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Updated: Jan 7, 2026

An Intravital Microscopy-Based Approach to Assess Intestinal Permeability and Epithelial Cell Shedding Performance
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质子抑制剂通过p38-MAPK/NF-κB信号通路增加了肠道上皮层的细胞透性

Meng Zhang1, Wei Liu1, Yunhui Liu1

  • 1Department of Infectious Diseases, Tongji Hospital, Tongji Medical College, State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Disease, Huazhong University of Science and Technology, 1095, Jiefang Avenue, Wuhan, 430030, Hubei Province, People's Republic of China.

Molecular biology reports
|December 10, 2025
PubMed
概括

质子抑制剂 (PPI) 通过通过p38-MAPK/NF-κB通路减少奥克卢丁的表达来增加肠道的透性. 这突显了PPI治疗对肠道屏障的潜在风险.

关键词:
肠道上皮层的细胞透性.质子抑制剂 质子抑制剂信号通道的信号通道.紧密结合蛋白质是紧密结合的蛋白质.

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