Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Psychosurgery01:30

Psychosurgery

1.3K
Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
1.3K
Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

434
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
434
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

5.8K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
5.8K
Drug Therapy01:28

Drug Therapy

226
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
226
Human Genetics01:28

Human Genetics

1.4K
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
1.4K
Treatment Strategies for Psychological Disorders01:24

Treatment Strategies for Psychological Disorders

559
Treatment approaches for psychological disorders fall into three main categories: psychological, biological, and sociocultural. Each approach targets different aspects of mental health, requiring varying levels of education and training.
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
559

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Monocyte abundance and glycolytic reprogramming associate with motivational impairment in depression.

Brain, behavior, and immunity·2026
Same author

Predicting Post-Radiotherapy Epigenetic Age Acceleration From Pre-Treatment Data Using a Machine Learning Framework in Head and Neck Cancer Patients.

Cancer medicine·2026
Same author

Depressive symptoms and perceived stress in patients with head and neck cancer undergoing intensity-modulated radiation therapy: A longitudinal study.

European journal of oncology nursing : the official journal of European Oncology Nursing Society·2026
Same author

Chronic pain in a modern virally suppressed HIV cohort is associated with disability and poorer mental health.

Scientific reports·2026
Same author

Inhibition of Cxcr4 chemokine receptor signaling improves habituation learning in a zebrafish model of neurofibromatosis.

Disease models & mechanisms·2026
Same author

Synaptic effects of interleukin-6 on human iPSC-derived dopaminergic neurons.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology·2026

相关实验视频

Updated: Jan 7, 2026

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

15.9K

在精神病学中实施精准医学.

Federico Cevoli1, Husseini K Manji2,3,4, Andrew H Miller5

  • 1Fondation FondaMental, Créteil, France.

JAMA psychiatry
|December 10, 2025
PubMed
概括

对神经精神疾病的药物发现需要一个范式的转变. 精准精神病学,由生物标志物发现和改革的临床试验驱动,为心理健康状况提供更有效的治疗方法.

更多相关视频

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
07:31

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack

Published on: May 15, 2020

7.5K
Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology
07:03

Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology

Published on: December 1, 2023

1.4K

相关实验视频

Last Updated: Jan 7, 2026

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

15.9K
Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
07:31

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack

Published on: May 15, 2020

7.5K
Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology
07:03

Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology

Published on: December 1, 2023

1.4K

科学领域:

  • 神经科学和精神病学 在
  • 翻译医学是一种翻译医学.

背景情况:

  • 神经精神疾病是全球健康的重大负担.
  • 在过去的50年里,在开发基于机制的精神疾病治疗方法方面取得的进展有限.
  • 现有的药物发现管道已经产生了很少的验证治疗方法.

研究的目的:

  • 确定精神障碍药物发现进展缓慢的原因.
  • 提出一个转向精确精神病学的范式转变.
  • 为推进精神病药物开发提出建议.

主要方法:

  • 审查精神病药物发现当前的挑战.
  • 分析开发基于机制的治疗方法有限成功的原因.
  • 讨论潜在的解决方案,包括生物标志物发现和临床试验改革.

主要成果:

  • 确定了阻碍心理疾病有效药物发现的关键障碍.
  • 建议过渡到精确精神病学,利用生物标志物进行向治疗.
  • 倡导改革临床试验方法,包括基于生物标志物的适应性设计.

结论:

  • 精准精神病学为开发神经精神疾病的新疗法提供了一个有前途的框架.
  • 生物标志物发现和创新的临床试验设计对于加速进展至关重要.
  • 增加投资和跨部门合作对于实现精准精神病学的潜力至关重要.