气管指数是否有用在怀疑甲状腺功能低下的婴儿中评估甲状腺?
Nursel Muratoglu Sahin1, Hasibe Gokce Cinar2, Behiye Sarikaya Ozdemir1
1Division of Pediatric Endocrinology, University of Health Sciences, Dr. Sami Ulus Obstetrics and Gynecology, Child Health and Diseases Training and Research Hospital, Ankara, Türkiye.
Journal of pediatric endocrinology & metabolism : JPEM
|December 10, 2025
概括
气管指数 (TI) 是对婴儿甲状腺大小的有用估计,与甲状腺体积 (TV) 相对应. 然而,它的准确性在早产婴儿,低出生体重婴儿和甲状腺增生病例中是有限的.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 新生儿成像学 新生儿成像学
- 甲状腺诊断 甲状腺诊断
背景情况:
- 在婴儿中评估甲状腺大小是具有挑战性的,因为他们的子很短.
- 气管指数 (TI) 提供了使用横向尺寸的替代测量方法.
- 之前的研究集中在婴儿的规范性TI数据上.
研究的目的:
- 在怀疑患有先天性甲状腺功能低下症的婴儿中评估气管指数 (TI) 的实用性.
- 在这个人群中评估TI和甲状腺体积 (TV) 之间的相关性.
主要方法:
- 包括80名患有新生儿查TSH水平升高的婴儿.
- 用甲状腺体积 (TV),电视标准偏差得分 (SDS) 和TI来评估甲状腺体大小.
- 统计分析检查了TI,电视和电视SDS之间的相关性.
主要成果:
- TI显示了与电视和电视SDS的正相关性 (r=0.381,p<0.0001;r=0.400,p<0.0001).
- 在早产婴儿 (<38周妊娠期) 或低出生体重 (<2,700g或<-1 SDS BW) 的婴儿中没有观察到TI和TV之间的相关性.
- 对于检测甲状腺增生症的TI的灵敏度和特异性分别为53.8%和65.7%.
结论:
- 在低甲状腺和正常婴儿中,TI对于估计甲状腺大小是有用的.
- 在早产婴儿和低出生体重婴儿中,TI与电视的相关性是有限的.
- 低灵敏度和特异性表明TI在评估特定婴儿群体的甲状腺增生时的有用性有限.
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