暴露与生物积累增加和精液质量下降有关:系统性审查和元分析
Victoria Ifeoluwa Adisa1,2, Precious Jesutofunmi Ashonibare1,2, Cecilia Adedeji Adegbola1,2
1Department of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.
JBRA assisted reproduction
|December 10, 2025
概括
暴露于会显著损害男性生殖健康,降低精子质量并增加异常. 这凸显了对减轻暴露和保护生育能力的干预措施的迫切需要.
科学领域:
- 环境健康 环境健康
- 生殖毒理学 生殖毒理学
- 人体精液质量分析分析
背景情况:
- 是一种有毒的重金属,已知对健康有不良影响.
- 职业和环境暴露是全球关注的问题.
- 了解对男性生育能力的影响对于公共卫生至关重要.
研究的目的:
- 系统地审查和元分析暴露对人类精液质量的影响.
- 探索对精子参数影响的潜在机制.
主要方法:
- 在Google学者,PubMed和Scopus (2024年3月至4月) 进行了系统的文献搜索.
- 根据PECOS模型标准选择的研究.
- 对包括17项研究的数据进行了元分析.
主要成果:
- 暴露个体的血液和精液中含量的升高得到证实.
- 观察到射精量,精子数,精子度和总运动率的显著下降.
- 暴露与异常精子形态显著增加有关.
结论:
- 暴露明显与人类精子质量降低有关.
- 迫切需要采取战略来减少环境和职业暴露.
- 对减轻毒性干预措施的进一步研究是有必要的.
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