建立儿科癌症队列并使用儿童癌症数据倡议工具访问数据
Subhashini Jagu1, Jaime M Guidry Auvil1, Mark Cunningham2
1Office of Data Sharing, National Cancer Institute, Rockville, MD.
JCO clinical cancer informatics
|December 10, 2025
概括
儿童癌症数据倡议 (CCDI) 为访问和分析各种儿童癌症数据提供了工具和资源. 这有助于研究改善儿童癌症的理解,治疗和治疗结果.
科学领域:
- 儿科瘤学 儿科瘤学
- 癌症基因组学 癌症基因组学
- 数据科学在医学中的数据科学
背景情况:
- 为了更好地了解儿童,青少年和年轻成人癌症,需要全面的数据共享.
- 国家癌症研究所的儿童癌症数据倡议 (CCDI) 通过提供广泛的癌症数据库来满足这一需求.
研究的目的:
- 概述在CCDI数据生态系统中查找,请求,访问,下载和分析数据的过程.
- 突出CCDI中心探索仪表板和儿童癌症临床数据共享 (C3DC) 在加速儿科癌症研究中的作用.
主要方法:
- 利用CCDI资源支持的基于队列的分析.
- 采用标准化数据模型进行研究,参与者,样本,诊断和治疗数据,以协作方式更新.
- 利用起草的儿科癌症核心常用数据元素列表为标准化研究参考.
主要成果:
- 该中心作为CCDI数据,工具和应用程序的中央接入点.
- C3DC提供了协调的参与者级临床数据,而CCDI Hub Explore Dashboard则对文件级数据进行了目录.
- 用户可以搜索,下载数据表,并使用协调,非识别参与者数据构建队列.
结论:
- CCDI强调数据的可访问性和互操作性,以促进儿科癌症研究的发现.
- CCDI的资源和数据支持数据驱动的洞察力,并加强儿童癌症研究社区的合作.
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