2001年至2022年间美国儿童和青少年癌症发病率趋势
Meredith S Shiels1, Anika T Haque2, Rena R Jones1
1National Cancer Institute, Rockville, MD, United States.
Cancer discovery
|December 10, 2025
概括
在2001-2022年间,儿童癌症发病率上升,然后下降. 虽然淋巴瘤的发病率增加,但白血病和中枢神经系统瘤的发病率呈现出不同的趋势. 诸如分类变化的因素影响了这些儿童癌症趋势.
科学领域:
- 流行病学 流行病学
- 儿科瘤学 儿科瘤学
- 公共卫生 公共卫生
背景情况:
- 儿童和青少年癌症发病率一直是一个日益严重的公共卫生问题.
- 了解时间趋势对于资源配置和干预策略至关重要.
研究的目的:
- 估计2001年至2022年美国儿童和青少年癌症发病率的年龄标准化趋势.
- 分析这个年龄组内的特定癌症类型轨迹.
主要方法:
- 利用来自美国癌症统计数据库的0-19岁个体的国家数据.
- 在不同时期 (2001-2016,2016-2022) 癌症发病率的计算年百分比变化.
主要成果:
- 儿童癌症的总体发病率增加了0.94%/年 (2001-2016),然后减少了0.96%/年 (2016-2022).
- 淋巴瘤的发病率持续增加 (0.49%/年),而白血病和中枢神经系统瘤的发病率呈现出特定时期的变化.
- 据估计,与2001年的比率相比,2022年有1040例多余的儿童癌症诊断发生.
结论:
- 儿童癌症发病率表现出复杂的时间动态,最初的上升随后下降.
- 观察到的趋势可能受到不断变化的癌症分类,诊断技术和查实践的影响.
- 对风险因素的进一步研究是有必要的,以了解和减轻儿童癌症负担.
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