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相关概念视频

Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

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The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
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Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

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The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
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X-ray Imaging01:24

X-ray Imaging

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German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...
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Mutations01:35

Mutations

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Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
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Mutations01:39

Mutations

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Overview
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X-ray Diffraction of Biological Samples01:10

X-ray Diffraction of Biological Samples

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X-ray diffraction or XRD is an analytical tool that utilizes X-rays to study ordered structures such as crystalline organic and inorganic samples, polycrystalline materials, proteins, carbohydrates, and drugs.
According to Bragg's law, when X-rays strike the sample positioned on a stage, the rays are  scattered by the electron clouds around the sample atoms. The  X-ray diffraction or scattering is caused by constructive interference of the X-ray waves that reflect off the internal...
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相关实验视频

Updated: Jan 9, 2026

Author Spotlight: Investigating Physiological Functions of Vitamin A Transporters Using HPLC-Based Vitamin A Profiling
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通过X射线介导的维生素D合成.

Julia Kühn1, Gabriele I Stangl1

  • 1Institute of Agricultural and Nutritional Sciences, Martin Luther University Halle-Wittenberg, Germany.

Food chemistry
|December 10, 2025
PubMed
概括

电离性X射线辐射可以将固醇前体转化为维生素D,为维生素D合成提供了一种新的方法. 这种意想不到的途径产生了大量的维生素D,相当于低剂量的紫外线B暴露.

科学领域:

  • 生物化学 生物化学
  • 辐射化学 辐射化学
  • 营养科学 营养科学

背景情况:

  • 维生素D的合成主要与紫外线B (UVB) 光暴露有关.
  • 像7-脱胆固醇和厄戈斯特醇这样的前体通过UVB辐射转化为维生素D2和维生素D3.

研究的目的:

  • 调查电离性X射线辐射诱导其前体维生素D形成的潜力.
  • 为了比较X射线照射与传统的UVB照射对维生素D合成的疗效.

主要方法:

  • 结晶和溶于油中的7-脱水胆固醇和埃尔戈斯特被X射线照射,剂量为25kGy.
  • 量化了维生素D的产量,并与在不同剂量 (20和200mJ/cm2) 的UVB照射中获得的产量进行了比较.
  • 在复杂的矩阵中也评估了X射线辐射的影响,如,酵母和动物料.

主要成果:

  • 在25kGy的X射线照射中,从晶体前体中产生了大量的维生素D3 (94μg/g) 和维生素D2 (74μg/g).
  • 当前体在油中溶解时,X射线暴露产生了70 ng/g的维生素D3和45 ng/g的维生素D2.
  • 来自X射线照射的维生素D产量与20mJ/cm2UVB的产量相当,尽管高剂量的UVB产量显著增加.

结论:

关键词:
食品灭菌 食品灭菌电离辐射辐射的电离辐射.紫外线是紫外线的光线.维生素D的合成方法这是X射线.

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  • 电离性X射线辐射代表了产生维生素D的新且未知的途径.
  • 这一发现为维生素D的生产和强化开辟了新的途径,特别是在食品和料应用中.