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Updated: Jan 9, 2026

Identification of Pharmaceuticals in The Aquatic Environment Using HPLC-ESI-Q-TOF-MS and Elimination of Erythromycin Through Photo-Induced Degradation
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Identification of Pharmaceuticals in The Aquatic Environment Using HPLC-ESI-Q-TOF-MS and Elimination of Erythromycin Through Photo-Induced Degradation

Published on: August 1, 2018

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埃索梅普拉在生物相关的二碳酸盐缓冲剂中的化学稳定性以及针对特定降解产品的探索性研究

Ayaka Takasusuki1, Takahiro Takayama2, Koichi Inoue2

  • 1Laboratory of Molecular Pharmaceutics, College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1, Nojihigashi, Kusatsu-shi, Shiga 525-8577, Japan.

Journal of pharmaceutical and biomedical analysis
|December 10, 2025
PubMed
概括

与酸盐缓冲溶液 (PPB) 相比,生物相关的二碳酸盐缓冲溶液 (BCB) 并没有改变埃索梅普拉的降解率. 然而,BCB显示了特定降解产品的丰富性增加,突出了缓冲区依赖的降解途径.

关键词:
双碳酸盐是一种二碳酸盐.生物相关的生物相关性化学降解 化学降解埃索梅普拉 (esomeprazole) 是一种药物.质谱测量质量谱测量稳定性测试 稳定性测试 稳定性测试

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