手术后的形出院预测了儿科低度发育和相关瘤的发作结果
Florian Mayer1, Johannes Zielke1, Birgit Pimpel1
1Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, a full Member of ERN EpiCARE, Austria.
概括
在为低度发育和相关瘤 (LEATs) 接受手术的儿童和青少年中,术后的间接性发性泄露 (iED) 可以预测长期发作的结果. 手术后监测iED频率变化对于预测发作复发至关重要.
科学领域:
- 儿科神经学 儿科神经学
- 手术 手术 手术
- 神经生理学 神经生理学
背景情况:
- 低度发育和相关瘤 (LEATs) 是儿童的重要原因.
- 手术是治疗LEAT儿童耐药性的常见治疗方法.
- 预测手术后的发作结果对于患者管理至关重要.
研究的目的:
- 评估术后视频脑电图 (EEG) 检测到的间接性形放电 (IED) 在患有LEAT的儿科患者的预后意义.
- 确定iEDs的存在和演变是否可以预测LEATs手术后的长期控制.
主要方法:
- 一个回顾性分析前期收集的手术前后视频EEG数据来自59名患有LEAT的儿科患者,他们接受了手术.
- 在手术后至少24个月评估iED特征 (存在,焦点,频率) 与结局之间的关联.
- 包括单变量和多变量模型在内的统计分析,以确定不良结果的独立预测因素.
主要成果:
- 在手术后的头12个月内,IED频率显著增加 (≥50%) 与不良的长期发作结果独立相关 (OR: 16.2,p=0.037).
- 3个月的二次IED焦点和12个月的持续IED的存在也与单变量分析中的不利结果有关.
- 术后随访的中位数为59个月,这表明对长期结果的评估是可靠的.
结论:
- 手术后的IED,特别是它们的时间演变,是儿童LEAT手术患者长期发作结果的有价值的预测指标.
- 对于LEAT患者的发作结果的预后模型应该包括iED存在和术后EEG的进展,以及临床,放射和手术因素.
更多相关视频
10:22Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy
Published on: December 6, 2016
21.0K
09:32Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
Published on: December 18, 2016
12.8K
相关概念视频
Epilepsy and Seizures: Overview
1.1K
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
1.1K
Seizures: Classification
1.3K
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
1.3K
