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在波兰本土,引入和养殖的类动物中病毒的传播
Sanna Tervo1, Andrzej Zalewski2, Hanna Vauhkonen3
1Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, 5 Agnes Sjöbergin katu 2, 00790, Helsinki, Finland; Department of Virology, Faculty of Medicine, University of Helsinki, Haartmaninkatu 3, 7 Helsinki, 00290, Finland.
Virology
|December 10, 2025
概括
美国子可以携带病毒,引发动物感染的担忧. 这项研究发现,在养殖的鱼群中,与阿列乌提亚鱼病病毒 (AMDV) 和鱼Torque teno neovison病毒 (mTTV) 共同感染,突出了监测需求.
科学领域:
- 兽医病毒学 兽医病毒学
- 野生动物疾病生态学 野生动物疾病生态学
- 动物感染病原体监测监测
背景情况:
- 美国 (Neogale vison) 是各种病毒的公认储存库,包括动物病原体.
- 它们与人类的生理和解剖学相似性,特别是肺部结构,表明它们在病原体传播中的潜在作用.
- 了解子和其他类动物的病毒动态对于评估跨物种疾病风险至关重要.
研究的目的:
- 调查波兰本土类动物和野生和养殖的美国子种群中病毒感染的流行程度和多样性.
- 评估SARS-CoV-2,阿列乌提人病病毒 (AMDV) 和鱼Torque teno neovison病毒 (mTTV) 传播和共感染的可能性.
- 分析检测到的病毒的遗传关系和传播模式.
主要方法:
- 收集和分析来自各种类物种 (2019-2022) 的血液和肺组织样本.
- 在270个血液样本中对SARS-CoV-2抗体进行血清检测.
- 使用PCR (129个肺样本) 和转基因组学 (37个肺样本) 检测病毒的分子检测.
- 病毒基因组的遗传学分析,以确定其起源和传播途径.
主要成果:
- 在野生的或野生类动物中没有检测到SARS-CoV-2;两只养殖明克的检测结果呈阳性.
- 在87.8%的子组织样本中检测到AMDV的26.4%,mTTV的87.8%,经常出现 coinfections.
- 三只动物同时感染了AMDV,mTTV和SARS-CoV-2.
- 遗传学分析表明AMDV的持久性和在养殖和野生子之间以及在养殖场之间传播.
- mTTV菌株显示了波兰和中国人口混合的证据.
结论:
- 养殖可以藏并可能传播多种病毒,包括SARS-CoV-2.
- 在子种群中,AMDV和mTTV非常普遍,有复杂的传播动态的证据.
- 该研究强调了加强养的监测和严格的生物安全措施的必要性,以减轻动物传染病威胁和跨物种病原体溢出.
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