长度变化萨科佩尼亚状态和心血管疾病风险和所有原因死亡率的长度变化
Kaixin Zhang1, Xiaowei Zheng2, Tao Ma3
1Department of Clinical Research Center, Wuxi No.2 People's Hospital (Jiangnan University Medical Center), Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, 214002, China.
Experimental gerontology
|December 10, 2025
概括
萨科佩尼亚状况的变化会影响心血管疾病 (CVD) 风险和死亡率. 对老年人心血管疾病预防策略来说,监测肉症进展是关键.
科学领域:
- 老年学是一门学科.
- 心血管医学 心血管医学
- 流行病学 流行病学
背景情况:
- 萨科佩尼亚是一种肌肉质量和力量的损失所表现的疾病.
- 石病状况的动态变化与诸如心血管疾病 (CVD) 和死亡率等健康结果之间的关联尚未得到充分理解.
- 这项研究调查了大队伍中 Sarcopenia 状态的演变与重大健康风险之间的联系.
研究的目的:
- 评估萨科佩尼病状况变化与心血管疾病发病率之间的关联.
- 评估萨科佩尼病状况变化与全因死亡率之间的关系.
- 提供基于肉症监测的针对性心血管疾病预防策略的见解.
主要方法:
- 利用了7257名中国健康与退休长度研究 (2011) 参与者的数据.
- 根据2019年亚洲麻症工作组 (AWGS 2019) 标准定义的麻症.
- 在2年的随访期间,使用Cox比例危险回归来分析对心血管疾病和死亡率的萨尔科佩尼亚状态 (从未,发病,缓解,持久) 的变化.
主要成果:
- 与没有皮症的个人相比,皮症改善或持续的人患心血管疾病风险增加 (HR分别为1.37和1.32).
- 改善和持续的萨科佩尼亚都与中风和心脏事件的风险增加有关.
- 患有基线可能的肉症的参与者恢复到非肉症状态时,新发性心血管疾病和中风的风险显著降低.
结论:
- 萨科佩尼亚状态的动态变化与发生心血管疾病和全因死亡率的各种风险有显著的关联.
- 长期监测sarcopenia状态对于有效预防心血管疾病至关重要.
- 这些发现强调了在老年护理和心血管健康中解决萨科佩尼亚的重要性.
相关概念视频
02:20Longitudinal Research
13.0K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
13.0K
01:26Longitudinal Studies
446
Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
446
01:09Changes in the Appendicular Skeleton with Age
3.3K
The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
3.3K
01:30Coronary Artery Disease I: Introduction
847
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
847
01:29Bone Disorders
5.0K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
5.0K
01:19The Effect of Aging on Tissues
3.1K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
3.1K