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Updated: Jan 9, 2026

Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles
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Published on: August 28, 2015

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开发基于低分子量甲基纤维素的塞鲁美替尼布载固体分散剂,以提高溶解性,稳定性,溶解性和生物可用性

Jun Hak Lee1, Jun-Pil Jee2, Hyeon Jae Kim3

  • 1College of Pharmacy and Inje Institute of Pharmaceutical Sciences and Research, Inje University, 197 Inje-ro, Gimhae, 50834, Republic of Korea.

International journal of biological macromolecules
|December 10, 2025
PubMed
概括

这项研究开发了一种改进的固体分散 (SD) 配方,用于使用甲基纤维素4 202fcP (MC 4 202fcP) 的甲基硫酸 (SEL),以克服不良溶解度和生物可用性. 新的SEL/MC 4 202fcP配方显著增强了大鼠的药物溶解,稳定性和口服吸收.

关键词:
生物可用性 生物可用性解散 解散 解散 是一个过程.甲基纤维素是什么 甲基纤维素是什么塞卢梅替尼布硫酸盐的使用情况固体的分散 固体的分散可溶性 溶解度 可溶性

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