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Updated: Jan 9, 2026

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由STAT5激活瘤基因诱导的 Kostatin M促进了血液性恶性瘤的疾病进展

Michael Rassner1, Tony Andreas Müller1,2, Kirstyn Anne Crossley1,3

  • 1Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Signal transduction and targeted therapy
|December 10, 2025
PubMed
概括

瘤基因突变激活 Kostatin M (OSM),驱动血液恶性瘤的进展和免疫抑制. 针对OSM信号提供了一个有前途的治疗策略,用于骨髓增殖性瘤和相关的血液癌症.

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