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本质上无序的区域促进了目标搜索,以通过酵母转录因子驱动促进体选择性

Nir Strugo1,2, Carmit Burstein1, Sk Saddam Hossain3

  • 1Faculty of Biology, Technion - Israel Institute of Technology, Haifa, Israel.

Nature communications
|December 10, 2025
PubMed
概括

像Msn2这样的转录因子中的内在无序区域有助于DNA结合和扫描. 这种由序列特异性相互作用驱动的机制,在没有染色质或辅因子的情况下增强了促进子选择性.

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