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Pla2g7通过Alox12/12-HETE/Gpr31信号轴调节骨质稳定

Jiayan Jin1,2, Zeyu Zheng1,2, Jiaxuan Gu3

  • 1Department of Orthopaedic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Nature communications
|December 10, 2025
PubMed
概括

脂酶A2组VII (Pla2g7) 促进骨质细胞分化,有助于骨质疏松症. 抑制Pla2g7或其通路可以改善骨质量,并可以治疗骨损失疾病.

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