异常的MLH1细胞质局部化标志着细胞群种植乳腺癌复发的种子

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Aloran Mazumder1,2, Jerry Dewitt1,2, Elena Oropeza1

  • 1Department of Biology, San Diego State University, San Diego, CA, USA.

Nature communications
|December 10, 2025
PubMed
概括

在雌激素受体阳性乳腺癌中MLH1的细胞质局部化驱动内分泌治疗耐药性. 这一发现表明CDK4/6抑制剂可能有利于患有这种特定MLH1失调的患者.

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