测定预计冲程体积变化的切断值,作为流体响应性的预测指标
Yukiko Yamazaki1, Shuko Matsuda1, Yuka Matsuki2
1Department of Anesthesiology and Reanimatology, Faculty of Medicine Sciences, University of Fukui Hospital, 23-3 Shimoaizuki, Matsuoka, Eiheiji cho, Yoshida gun, Fukui, 910-1193, Japan.
BMC anesthesiology
|December 10, 2025
概括
该研究确定了估计中风体积变化 (esSVV) 的切割值为7.3%,这是流体响应的非侵入性指标. 这一发现为在循环管理中使用esSVV提供了临床值.
科学领域:
- 麻醉学和重症监护医学
- 心血管生理学心血管生理学
- 医疗技术评估 医疗技术评估
背景情况:
- 估计中风体积变化 (esSVV) 是一个非侵入性流体响应指标,来自估计连续心脏输出 (esCCO) 系统.
- 缺少esSVV的最终切割值,阻碍了其临床应用.
- 这项研究旨在确定esSVV的可靠切割值.
研究的目的:
- 为了确定esSVV的最佳切割值作为流体响应的指标.
- 为了验证esSVV在管理循环状态中的临床实用性.
- 为esSVV解释提供一个定量值.
主要方法:
- 一项前性观察性研究,包括接受全身麻醉的患者.
- 校准esCCO系统并记录基线血压.
- 在静脉压力下降>10%后,用ESVV测量输注前后的液体挑战剂 (300毫升合物) 给药.
主要成果:
- 对于esSVV,接收器运行特征曲线 (AUC) 下的面积为0.73.
- 对于esSVV的值为7.3%,证明了最佳的灵敏度和特异性.
- 对SVV的确定的切线为12% (AUC为0.65).
结论:
- 对于esSVV的确定的切割值为7.3%.
- 由于其已建立的切断值,esSVV是循环管理的宝贵工具.
- 这为指导流体治疗决策提供了一个关键参数.
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