认知行为治疗脱人化-脱现障碍 (CBT-f-DDD):一个可行性随机试验
Elaine C M Hunter1, Lucy Ring2, Rafael Gafoor3
1Division of Psychiatry, University College London, London, UK. e.hunter@ucl.ac.uk.
Pilot and feasibility studies
|December 10, 2025
概括
适应脱人化-脱现障碍 (CBT-f-DDD) 的认知行为疗法显示出希望. 这项可行性研究表明,CBT-f-DDD是一种可行的治疗选择,尽管未来的试验需要对研究设计进行改进.
科学领域:
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
- 心理健康研究 心理健康研究
背景情况:
- 脱人格化-脱现障碍 (DDD) 涉及对自我或环境持久的不真实的感觉.
- 适应DDD的认知行为疗法 (CBT-f-DDD) 在临床审计中已证明有效.
- 这项研究旨在评估CBT-f-DDD的可行性和可接受性.
研究的目的:
- 评估CBT-f-DDD对DDD成年参与者的可行性和可接受性.
- 收集关于CBT-f-DDD的有效性和健康经济学的初步数据.
- 为未来最终随机对照试验 (RCT) 的设计提供信息.
主要方法:
- 一个个别随机设计,比较成年DDD患者的CBT-f-DDD与常规治疗 (TAU).
- 被训练有素的治疗师在六个月内提供了CBT-f-DDD.
- 可行性目标包括招聘,保留,资源使用,代表性,可接受性,初步响应和健康经济学. 进行了定性采访.
主要成果:
- 在13个月内招募了30名参与者,63%完成了最终评估,表明需要改善保留.
- 研究设计和干预被认为是可以接受的,受试者和临床医生给予了积极的定性反.
- 与TAU组 (5.5分) 相比,CBT-f-DDD组的非个性化得分平均下降幅度更大 (16.9分). 卫生经济学分析表明,节省了成本,改善了质量调整后寿命.
结论:
- CBT-f-DDD是一种可行的治疗方法,用于治疗非个性化-非现实化障碍.
- 这项研究为CBT-f-DDD的更大,更明确的RCT提供了基础.
- 对于未来的研究,建议对研究设计和干预交付进行改进.
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