[使用粘合剂消灭主要的静脉 (多中心比较研究) ]
E V Shaydakov1, A B Sannikov2, S M Belentsov3
1Petrozavodsk State University, 185910, Petrozavodsk, Russian Federation.
Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery
|December 11, 2025
概括
一种新的俄罗斯粘合剂,Sulfacrylate,证明了与Medtronic VenaSeal系统可比的安全性和有效性. 这种国内的烯酸提供了分阶段的生物降解和更低的成本,在改善生活质量和静脉封闭方面证明不劣.
科学领域:
- 血管外科 血管外科
- 医疗器械技术 医疗器械技术
- 生物材料科学 生物材料科学
背景情况:
- 静脉是一种常见的血管疾病,需要有效的治疗.
- 烯酸粘合剂为内静脉消灭提供了一种最小侵入性的选择.
- 像VenaSeal这样的现有外国系统使用基于丁的烯酸.
研究的目的:
- 为了比较一个新的俄罗斯烯酸 (硫烯酸) 与Medtronic VenaSeal系统的临床结果.
- 评估硫烯酸盐在内静脉静脉消退治疗的安全性和有效性,长达一年的时间.
- 评估合成差异 (乙烯与butan) 和它们的临床影响.
主要方法:
- 临床比较研究涉及73名患者 (VenaSeal) 和75名患者 (Sulfacrylate).
- 根据CEAP,患者呈现了C2-C3临床类.
- 评估结果包括,疼痛 (VAS),生活质量 (CIVIQ-2) 和静脉封闭 (超声双重血管扫描) 在术后长达1年的时间.
主要成果:
- 国内的硫酸粘合剂被证明是安全的,并且在静脉内消灭方面非常有效.
- 硫酸盐在改善生活质量,控制炎症反应和实现静脉封闭方面表现为VenaSeal的非劣势.
- 硫烯酸盐的主要优点包括分阶段生物降解,完整的结缔组织消灭,以及更低的手术成本.
结论:
- 俄罗斯开发的硫烯酸是一种安全有效的替代品,用于治疗静脉.
- 硫酸盐的临床结果与已建立的VenaSeal系统相提并论.
- 国内的粘合剂在生物降解概况,成本效益和最终消灭质量方面具有显著的优势.
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