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Updated: Jan 9, 2026

Expression and Purification of the Human Lipid-sensitive Cation Channel TRPC3 for Structural Determination by Single-particle Cryo-electron Microscopy
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Published on: January 7, 2019

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C-终端PKC酸化对TRPC6电流动力学的影响

Maximilian Keck1, Sebastian Pöll1, Hannah Schmelzer1

  • 1Walther Straub Institute of Pharmacology and Toxicology, Ludwig Maximilian University of Munich, 80336 Munich, Germany.

International journal of molecular sciences
|December 11, 2025
PubMed
概括

蛋白激酶C (PKC) 酸化的短暂受体潜在的正规6 (TRPC6) 通道微调他们的活动. 修改TRPC6通道上的PKC位点会影响它们的门动力学和导电性,为相关疾病的药物开发提供了洞察力.

关键词:
通过PKC的酸化.在 TRPC6 频道.电流动力学是当前的动力学.摄影药理学 摄影药理学可光开关的激活器

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