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Updated: Jan 9, 2026

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
11:45

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles

Published on: August 22, 2018

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通过循环添加和环扩张合成1,3-氨酸和1,4-氨酸衍生物

Márta Palkó1, Nóra Becker1, Edit Wéber2,3

  • 1Institute of Pharmaceutical Chemistry, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.

International journal of molecular sciences
|December 11, 2025
PubMed
概括

研究人员开发了一种新的短合成方法,用于罕见的N,S-异环环,包括1,3-thiazines和1,4-thiazepines. 这种方法有效地创建了具有高 diastereoselectivity 的多个奇拉中心,通过先进的光谱和晶体技术得到证实.

关键词:
1,3-亚酸盐的含量为1,4-提亚泽类药物阿尔肯斯 (Alkenes) 是一种类型.这是一个循环加法循环.异质-DielsAlder反应反应在β-lactams中使用.

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