两性多 ((N-vinylpyrrolidone) 生物复合物与博尔特佐米布和DR5-选择性 TRAIL 变体:胰腺癌治疗的有希望的方法

Ekaterina Kukovyakina1, Alina A Isakova1,2,3, Dmitry Bagrov2

  • 1Department of Technology of Chemical, Pharmaceutical and Cosmetic Substances, D. Mendeleev University of Chemical Technology of Russia, 125047 Moscow, Russia.

概括

携带博特佐米布 (BTZ) 和 TRAIL 变体的新型生物复合物显示出对 pH 响应的药物释放. 这些纳米载体有效地抑制胰腺癌的生长,并诱导细胞亡,对健康细胞的毒性最小.

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