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Updated: Jan 9, 2026

Author Spotlight: Integrating BRET-Based Assays and Rare Mutation Analysis to Decipher RAF Kinase Regulation in Live Cells
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在黑色素瘤细胞中,NRas纳米集群介导BRAF/ERK和PI3K/AKT信号之间的交叉交互

Oren Yakovian1, Julia Sajman1,2, Eilon Sherman1

  • 1Racah Institute of Physics, The Hebrew University, Jerusalem 91904, Israel.

International journal of molecular sciences
|December 11, 2025
PubMed
概括

NRas蛋白与PI3K和BRAF形成纳米集群,影响黑色素瘤细胞信号传递和增殖. 抑制这些相互作用为癌症提供了潜在的治疗策略.

关键词:
在 AKT AKT 里面.在PI3K中,PI3K是指PI3K.拉斯拉斯拉斯拉斯拉斯拉斯 拉斯拉斯拉斯拉斯拉斯拉斯拉斯拉斯黑色素瘤是一种黑色素瘤.蛋白质聚类蛋白质的聚类.单个分子定位显微镜显微镜超分辨率显微镜的显微镜.

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