星球健康饮食中的生物活性营养成分,用于预防sarcopenic肥胖和糖尿病sarcopenia:系统性审查
Lia Elvina1,2, Chiao-Ming Chen3, Dang Hien Ngan Nguyen4
1School of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei 11031, Taiwan.
Nutrients
|December 11, 2025
概括
星球健康饮食 (PHD) 和其对齐的营养素可以帮助管理型肥胖症 (SO) 和糖尿病型肥胖症 (DS). 这些干预措施通过增强营养感应和线粒体效率来改善肌肉健康和代谢功能.
科学领域:
- 营养科学 营养科学
- 代谢健康 代谢健康
- 肌肉骨系统疾病 肌肉骨系统疾病
背景情况:
- 肥胖症 (SO) 和糖尿病性肥胖症 (DS) 是复杂的代谢肌肉骨疾病.
- 这些疾病包括过多的脂肪,胰岛素耐药性和肌肉衰竭.
- 星球健康饮食 (PHD) 提供了一种可持续的,植物向前的营养方法.
研究的目的:
- 系统地审查与PHD一致的饮食和生物活性营养干预措施.
- 评估它们对SO和DS的肌肉质量,力量和新陈代谢的影响.
- 探索这些干预的潜在机制.
主要方法:
- 按照PRISMA指南 (2015-2025) 进行系统审查.
- 在PubMed,Scopus和谷歌学者中搜索相关研究.
- 包括饮食,营养或补充剂干预在肥胖/糖尿病相关的条件.
主要成果:
- 分析了91项研究,按干预类型分类.
- 生物活性化合物 (例如,白醇,欧米茄-3,益生菌) 改善了肌肉质量,力量和线粒体功能.
- 这些机制涉及AMPK-SIRT1-PGC-1α和Akt-mTOR信号传递,增强胰岛素敏感性和减少蛋白质分解.
结论:
- 与PHD结合的食物 (植物蛋白,多,发酵产品) 支持营养感应和线粒体效率.
- 这些饮食模式为管理SO和DS提供了可持续的框架.
- 干预措施促进细胞弹性和肠道肌肉沟通.
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