病的眼部表现:当前的证据和临床影响
Monika Senterkiewicz1, Anna Szaflarska-Popławska2, Bartłomiej J Kałużny3
1Department of Ophthalmology, Collegium Medicum, Nicolaus Copernicus University in Torun, ul. Ujejskiego 75, 85-168 Bydgoszcz, Poland.
性疾病 (CD) 显著增加了眼睛疾病 (如白内障和脑膜炎) 的风险. 营养缺乏和微血管变化也会导致CD患者的视力问题.
科学领域:
- 眼科医生 眼科 眼科
- 胃肠病学 胃肠病学
- 免疫学 免疫学 免疫学
背景情况:
- 乳病 (CD) 是一种自身免疫性疾病,在遗传敏感的个体中由质触发.
- 除了胃肠道问题,CD还会影响肠外器官,尤其是眼睛.
- 眼部表现越来越被认为是CD中显著的并发症.
研究的目的:
- 审查和综合目前关于眼部参与乳病的证据.
- 要突出与CD相关的眼科疾病的范围.
- 为了告知临床实践关于CD患者的眼睛健康.
主要方法:
- 在PubMed,Cochrane,Web of Science和Scopus数据库中进行全面的文献搜索,截至2025年4月.
- 包括大量基于人口的队列,横截面和病例控制研究.
- 分析报告关于CD的催膜,眼睛结构和视觉功能的研究.
主要成果:
- 在患有CD的人群中,白内障和脑膜炎的风险增加.
- 眼膜不稳定的证据 (减少了撕裂时间,希尔默测试值).
- 眼部发现包括前腔体尺寸的减少,胸腔体厚度的改变,视网膜神经纤维层的稀薄以及微血管变化. 维生素缺乏 (A,D,B12,铁) 与这些变化有关.
结论:
- 疾病的眼部并发症是由于免疫失调,营养缺陷和微血管变化造成的.
- 对于患有眼睛症状的CD患者,建议进行眼科评估.
- 及时诊断和监测对于视觉结果和眼部发育至关重要.
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