在PET/CT上标准视觉和常规冠状动脉评分:与Agatston评分和预后影响的协议
Sehyun Pak1, Hye Joo Son2, Dongwoo Kim3
1Department of Medicine, Hallym University College of Medicine, Chuncheon 24252, Gangwon, Republic of Korea.
在PET/CT扫描上对冠状动脉 (CAC) 的视觉评估可靠且具有预后性. 这种方法可以准确预测癌症患者的主要不良心血管事件 (MACE).
科学领域:
- 心血管成像 - 心血管成像
- 核医学就是核医学.
- 放射学 放射学是一门学科.
背景情况:
- 在未完成的CT扫描上对冠状动脉 (CAC) 的视觉评估尚未得到充分证实.
- 它的可靠性在PET/CT中是不确定的,因为低剂量CT和文物.
- 临床实用性需要进一步调查.
研究的目的:
- 评估视觉CAC评分的可靠性和临床实用性,在未经检测的PET/CT扫描上.
- 为了将视觉CAC得分与ECG-gated CT Agatston得分进行比较.
- 评估视觉CAC评分对主要不良心血管事件 (MACE) 的预后价值.
主要方法:
- 对106名接受PET/CT和ECG通道CT的患者进行了回顾性分析.
- 六个读者使用视觉和顺序尺度对PET/CT进行CAC评估.
- 计算了观察者间的一致性和与心电图启动的CT Agatston分数的一致性.
- 主要不良心血管事件 (MACE) 在3.5年的中位随访期间被跟踪.
主要成果:
- 在视觉 (κ=0.761) 和顺序 (κ=0.779) 两种尺度上都观察到良好的观察者间一致.
- 对视觉尺度 (κ=0.849, κ=0.750) 的一致性与ECG-gated CT Agatston类别的一致性高于PET/CT Agatston类别 (κ=0.464).
- 在PET/CT上严重的CAC预测了MACE (HRs:4.41视觉,6.59顺序),顺序尺度分层MACE无生存率 (p=0.047).
结论:
- 视觉CAC评分不加的PET/CT是快速的,可重复的,并反映了ECG-gated CT的Agatston分级.
- 这种方法为癌症患者的MACE提供了预后价值.
- 在PET/CT上进行视觉CAC评分是一个临床上有用的工具.
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