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增加的担忧与自我报告,但不是告密者报告的主观认知衰退相关,预测事件痴呆症的风险增加.

Katya T Numbers1, Ben C P Lam2, Suraj Samtani1

  • 1Centre for Healthy Brain Ageing (CHeBA), Discipline of Psychiatry & Mental Health, School of Clinical Medicine, Faculty of Medicine & Health, University of New South Wales, Sydney 2052, Australia.

Diagnostics (Basel, Switzerland)
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概括

主观认知投诉 (SCC) 预测痴呆风险. 随着时间的推移,参与者越来越关注这一风险,这显着提高了这一风险,突出了对早期检测的纵向监测的重要性.

关键词:
痴呆症的风险 痴呆症的风险举报人报告,举报人报告.纵向轨迹是指纵向轨迹的纵向轨迹是指纵向轨迹的纵向轨迹.主观认知问题是主观认知问题.主观认知衰退 主观认知衰退

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科学领域:

  • 神经科学是一个神经科学.
  • 老年学是指老年学的学科.
  • 认知心理学 认知心理学

背景情况:

  • 主观认知投诉 (SCC) 是未来痴呆症的关键预测因素.
  • 该SCD-plus框架突出了认知关注和告知者的证实.
  • 有限的研究已经探索了SCC关注的纵向变化.

研究的目的:

  • 评估基线SCC关注及其纵向轨迹是否预测10年内发生的痴呆症.
  • 为了区分参与者与 SCC 关注的告密者报告的预测值.
  • 调查不断演变的主观认知经验的预后意义.

主要方法:

  • 潜增长曲线建模分析了873名老年人 (平均年龄为78.65) 的SCC关注.
  • 考克斯的比例危险模型在10年内检查了痴呆症风险.
  • 对人口统计和临床因素进行控制的分析.

主要成果:

  • 基线参与者和告知者SCC关注独立预测的痴呆症.
  • 随着时间的推移,越来越多的参与者对SCC的担忧显著增加了痴呆症风险 (HR=10.23).
  • 报告人关注度的变化并没有显著改变痴呆症风险预测.

结论:

  • 参与者和 SCC 关注的告知者提供了对痴呆风险的独特预后信息.
  • 监测参与者关注的纵向变化对于痴呆症风险评估至关重要.
  • 演变的主观认知经验可能表明潜在的病理变化,支持临床实用性.