糖尿病神经病变与2型糖尿病患者平衡障碍之间的关联:一个跨部分研究
Bianca Iliescu1,2, Andreea Herascu1,3,4,5, Laura Gaita3,4,5
1Doctoral School of Medicine, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Journal of clinical medicine
|December 11, 2025
概括
2型糖尿病患者的糖尿病神经病变 (DN) 显著损害了平衡,增加了对跌倒的恐惧. 神经病变的严重程度,特别是患者报告的症状,与更糟糕的结果相关,而运动功能显示没有关联.
科学领域:
- 神经学 神经学
- 内分泌学 在内分泌学.
- 老年病的医生 老年病的医生
背景情况:
- 糖尿病神经病变 (DN) 是2型糖尿病 (T2DM) 的常见并发症.
- DN可以影响平衡和步态,增加老年T2DM患者的跌倒风险.
- DN存在/严重程度与平衡,移动性和跌倒恐惧之间的关系需要进一步研究.
研究的目的:
- 评估糖尿病神经病变与平衡/运动障碍之间的关联.
- 评估T2DM患者糖尿病神经病变和跌倒恐惧之间的联系.
- 为了确定神经病变的严重程度是否预测平衡,移动性和跌倒恐惧.
主要方法:
- 124名T2DM成年人接受了神经病变评估 (密歇根州神经病变查仪器[MNSI],SUDOSCAN).
- 衡量平衡和跌倒风险是使用伯格平衡量表 (BBS),定时上升和上升 (TUG),布效率量表-国际 (FES-I) 和恐惧跌倒问卷-修订 (FFQ-R) 进行的.
- 统计分析包括比较,相关性和多变量线性回归.
主要成果:
- 与非DN患者相比,DN患者表现出更差的平衡 (较低的BBS) 和更大的跌倒恐惧 (更高的FES-I,FFQ-R).
- 较高的MNSI分数 (问卷和目标) 独立预测了较低的BBS和较高的TUG.
- 两个MNSI组件都预测了FES-I和FFQ-R得分的增加,这表明人们更担心下降.
结论:
- 糖尿病神经病变与T2DM患者的平衡受损和降落恐惧增加有显著的关联.
- 神经病症负担,特别是主观症状,与较差的身体表现和信心相关.
- 仅仅是超运动障碍似乎不会影响平衡,移动性或对跌倒的恐惧.
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