口服营养补充剂的坚持和血液透析患者的营养结果 - 一项前性研究
Lea Katalinic1, Ivana Juric1, Armin Atic1
1Department of Nephrology, Arterial Hypertension, Dialysis and Transplantation, University Hospital Centre Zagreb, 10000 Zagreb, Croatia.
Journal of clinical medicine
|December 11, 2025
概括
口服营养补充剂 (ONS) 的坚持在血液透析 (HD) 患者中较低,受性别和抑郁症等因素的影响. 虽然营养教育有助于一些人,但人类计量标记器预测死亡率.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 营养科学 营养科学
- 临床医学 临床医学
背景情况:
- 蛋白质能量浪费 (PEW) 影响高达75%的血液透析 (HD) 患者.
- 对于HD患者服用口服营养补充剂 (ONSs) 的了解很少.
- 这项研究调查了ONS的坚持,影响因素和24个月的临床结果.
研究的目的:
- 评估慢性HD患者的ONS坚持模式.
- 确定与ONS遵守相关的社会人口和心理因素.
- 评估ONS遵守和营养教育对临床结果的影响.
主要方法:
- 对101名HD患者进行了长达24个月的前性研究.
- 使用莫里斯基药物坚持度表 (MMAS-4) 评估坚持.
- 评估抑郁症状 (BDI),营养状况 (MIS,人类学) 和实验室标记.
主要成果:
- 50.5%的人报告定期使用ONS; 36.6%的人表示高度坚持 (MMAS-4=0).
- 遗忘和不良影响是主要的坚持障碍.
- 坚持与男性性别,抑郁症 (BDI) 有负相关性,与教育水平有正相关性.
- 使用ONS的患者的营养状况有所改善 (MIS降低,血红蛋白升高,MUAC).
- 营养教育改善了坚持和保存瘦组织质量,但对一些子组来说不足.
- 低的MUAC和三肌皮厚度预测死亡率.
结论:
- 在HD患者中,ONS的坚持仍然低于最佳水平.
- 个性化营养教育可以改善一些患者的结果,但并非所有患者.
- 人类测量标记是强烈预测HD患者死亡率的指标.
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