为结肠直肠癌建立一个救援内镜电穿孔 (SEE) 服务:国王的临床实施协议
Ademola Adeyeye1,2,3, Amyn Haji1,2
1King's College Hospital NHS Foundation Trust, London SE5 9RS, UK.
Journal of clinical medicine
|December 11, 2025
概括
内镜电穿孔 (EE) 为结直肠癌 (CRC) 提供了一种新的微创治疗方法,使用电脉冲和化疗. 本研究概述了救援内镜电穿孔 (SEE) 服务的标准化协议,以改善患者的治疗结果.
科学领域:
- 在瘤学瘤学.
- 最少侵入性的手术
- 医疗技术 医疗技术 医学技术
背景情况:
- 内镜电穿孔 (EE) 使用电脉冲和化疗治疗结直肠癌 (CRC) 瘤细胞死亡.
- 对于不适合手术的患者来说,EE在救援疗法,局部控制和息方面表现有前途.
- 这种疗法是根据皮肤癌的电化学疗法方案进行的.
研究的目的:
- 建立CRC中救援内镜电穿孔 (SEE) 服务的第一个全面和标准化的协议.
- 该协议涵盖了患者选择,程序步骤,设备和后续护理.
- 其目的是指导结直肠癌中SEE的临床实践.
主要方法:
- 基于欧洲电化学疗法标准操作程序 (ESOPE) 和临床证据的协议开发.
- 使用了经CE认可的ePORE®电穿孔发生器和EndoVE®探头.
- 详细的基础设施,治疗,安全和患者管理策略.
主要成果:
- 瘤评估包括临床,内镜和放射学评估.
- 在镇静下安全地进行了EE,实现了有效的局部瘤反应.
- 患者经历了症状缓解和生活质量的改善.
结论:
- 新的协议为在CRC中实施SEE服务提供了实际框架.
- 它促进了一致性,安全性和改善了患者的治疗结果.
- 未来的研究将完善指示,并将SEE纳入CRC管理途径.
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