在儿科患者的先天性胃肠道形结果和大致无症状的SARS-CoV-2感染之间的关联-系统性审查
Iulia Stratulat-Chiriac1, Elena Țarcă2, Raluca Ozana Chistol3
1Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Journal of clinical medicine
|December 11, 2025
概括
患有先天性胃肠道形和经手术后的SARS-CoV-2感染的儿科患者通常会经历轻度疾病和良好的外科手术结果. 如果保持感染控制,COVID-19阳性不应延迟必要的手术.
科学领域:
- 儿科手术 儿科手术
- 传染性疾病 传染性疾病
- 胃肠病学 胃肠病学
背景情况:
- 关于患有先天性胃肠道形和经手术后的SARS-CoV-2感染的儿童手术后果的证据有限.
- 了解这些结果对于在疫情期间管理儿科外科病例至关重要.
研究的目的:
- 系统地审查和分析关于患有先天性胃肠道形并同时感染SARS-CoV-2的儿童手术结果的科学证据.
- 评估外科手术期间的SARS-CoV-2感染对这一儿科患者群体手术结果的影响.
主要方法:
- 来自PubMed和Embase的观察性研究的系统综述 (至2024年8月).
- 包括报告有关患有先天性胃肠道形和SARS-CoV-2状态的儿童数据的研究.
- 使用Joanna Institute (JBI) 检查清单进行质量评估,并遵守PRISMA指南.
主要成果:
- 包括8项涉及29名儿科患者的研究;大多数是新生儿 (75%) 患上部 (62%) 或下部 (38%) 胃肠道异常.
- 大多数情况下,SARS-CoV-2感染是通过例行查 (>95%) 检测到的.
- 85%的患者被送回家;没有观察到与COVID-19相关的直接手术死亡率或重大并发症,尽管发生了常规发病率.
结论:
- 患有先天性胃肠道形和经手术后的SARS-CoV-2感染的儿科患者通常患有轻度疾病,并取得良好的外科手术结果.
- 当感染控制措施到位时,SARS-CoV-2阳性不应阻碍必要的外科干预.
- 进一步标准化,多中心研究是必要的,以完善这个队列的术后风险评估和管理策略.
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