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Updated: Jan 9, 2026

A Quantitative Measurement of Reactive Oxygen Species and Senescence-associated Secretory Phenotype in Normal Human Fibroblasts During Oncogene-induced Senescence
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打破pH代码:酸化触发SASP和细胞衰老中的炎症

Akimitsu Konishi1

  • 1Department of Biochemistry, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Shimotsuga-gun, Tochigi, 321-0293, Japan.

Journal of biochemistry
|December 11, 2025
PubMed
概括

由代谢变化驱动的细胞内酸化促进细胞衰老和炎症. 这项研究揭示了降低pH值如何激活与糖解相关的炎症电路,影响与年龄相关的慢性炎症.

关键词:
细胞衰老 细胞衰老葡萄糖溶解是什么? 葡萄糖溶解炎症 炎症是一种炎症.细胞内酸性化 细胞内酸性化老化相关的分泌表型 (SASP)

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