以模型为指导的化学环境和代谢网络设计,将途径与细胞适应性结合起来

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Natalia Kakko von Koch1, Tuula Tenkanen2, Sandra Castillo2

  • 1Aalto University, School of Chemical Engineering, Department of Bioproducts and Biosystems, Espoo, Finland.

Metabolic engineering communications
|December 11, 2025
PubMed
概括

一种新的方法,EvolveXGA,使用代谢模型来指导适应性实验室进化 (ALE),以改善微生物中的异质化合物生产. 这种方法与细胞适应性结合了所需的特征,加速了生物技术的菌株优化.

关键词:
适应性实验室进化的演变.遗传算法 遗传算法 遗传算法基因组规模的代谢模型葡萄糖酸是什么? 葡萄糖酸是什么?

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