在SARS-CoV-2感染中分析膜液属性:系统性审查
Roi Soto-Feijóo1, Elisa Landín1, Honorio Martínez-Martínez1
1Pulmonology Department, University Clinical Hospital of Santiago de Compostela, Santiago de Compostela, Spain.
Journal of thoracic disease
|December 11, 2025
概括
在重症急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 患者中,胸腔溢液 (PE) 在男性中很常见,并且通常是单边的. 这种情况表明预后不佳,并且与2019年冠状病毒病 (COVID-19) 病例的死亡率增加有关.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 在严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 感染中,胸腔液 (PF) 的特征尚不清楚.
- 在2019年冠状病毒病 (COVID-19) 患者中报告了多流液 (PE),但缺乏确的特征.
研究的目的:
- 系统地审查和总结有关SARS-CoV-2感染患者肺部液体属性的现有证据.
- 分析COVID-19中PE的PF特征和PE治疗策略.
主要方法:
- 按照PRISMA方法论进行系统的文献搜索.
- 包括18篇文章,详细介绍了SARS-CoV-2患者的PF特征和PE治疗.
- 分析了来自32名患者和37名PF样本的数据.
主要成果:
- 腹腔溢出 (PE) 主要影响男性 (5.4:1比),年龄中位数为61岁,通常单边 (71.4%) 和大.
- PF分析显示出排泄液 (88.9%) 的外观有变化 (血清性,血性,性) 和主要是中性友的透.
- SARS-CoV-2 PCR在26.1%的PF样本中呈阳性;COVID-19患者的PE与40%的死亡率有关.
结论:
- 与COVID-19相关的PE在50-80岁的男性中更为常见,通常单边和大.
- 在COVID-19中,PF表现出排泄性,中性友好性特征,需要标准的PE治疗.
- 在COVID-19中,PE意味着预后指标不佳,与死亡率增加相关.
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