由于COVID-19大流行,肺体积减小手术的延迟:对患者表现和死亡率的影响
Alberte Lund1, Henrik J Hansen1, Kåre Hornbech1
1Department of Cardiothoracic Surgery, Rigshospitalet, Copenhagen, Denmark.
Journal of thoracic disease
|December 11, 2025
概括
在COVID-19大流行期间推迟的肺体积减小手术 (LVRS) 恶化了患者的结果,包括肺功能和运动能力. 及时的手术干预对于严重慢性阻塞性肺病 (COPD) 患者至关重要,以防止死亡率和病情恶化.
科学领域:
- 肺部医学 肺部医学
- 手术瘤学手术瘤学
- 流行病学 流行病学
背景情况:
- 严重的慢性阻塞性肺病 (COPD) 是渐进的,并与高死亡率有关.
- 由于COVID-19大流行,手术推迟发生了很大程度,影响了各种医疗治疗.
- 延迟肺体积减小手术 (LVRS) 的后果仍然被低估.
研究的目的:
- 评估由于COVID-19大流行而推迟LVRS对患者健康和手术候选人的影响.
- 为了评估治疗延迟后肺功能,运动能力和症状负担的变化.
主要方法:
- 追溯观察性研究包括LVRS患者,由于COVID-19延期≥6个月.
- 从机构数据库中收集的数据,包括肺功能测试,6分钟步行测试 (6MWT) 和血液气体分析.
- 评估症状,死亡率,感染和多学科团队 (MDT) 对外科适应性的重新评估.
主要成果:
- 67名患者经历了LVRS延迟;16%的人感染了COVID-19.
- 观察到强迫呼吸量在一秒内 (FEV1) 和6MWT性能显著下降.
- 氧度降低和症状增加;在重新评估前发生6%的死亡率.
结论:
- 在严重的COPD患者中,LVRS延迟了负面影响的肺功能,运动耐受性和氧气和.
- 推迟导致由于临床恶化和等待名单死亡率增加而取消手术.
- 优先考虑及时的LVRS对于这个脆弱的患者群体来说至关重要,以减轻不良结果.
关键词:
冠状病毒疾病2019年 (COVID-19) 是一个疾病.慢性阻塞性肺病 (COPD) 是一种慢性阻塞性肺病.在治疗中延迟治疗.突发性质炎症是什么意思肺体积缩小手术 (LVRS) 是一种手术.更多相关视频
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