一个"buckshot"转移性黑色素瘤病例:一种罕见且具有攻击性的皮肤传播模式
Nicole Werpachowski1, Caroline Carr2
1Lenox Hill Hospital, Northwell Health, New York, USA.
SAGE open medical case reports
|December 11, 2025
概括
转移性黑色素瘤甚至可以发生在负的哨兵淋巴结活检后. 这一案例凸显了对高风险黑色素瘤患者的勤奋随访的关键需求,以检测晚期复发.
科学领域:
- 在瘤学瘤学.
- 皮肤病学 皮肤病学
- 手术病理学手术病理学
背景情况:
- 黑色素瘤是一种具有高死亡率的侵袭性皮肤癌.
- 早期检测对于改善患者的治疗结果至关重要.
- 哨兵淋巴结活检 (SLNB) 是黑色素瘤的一个关键分期程序.
研究的目的:
- 要呈现一个转移性黑色素瘤病例,负SLNB.
- 审查与黑色素瘤阶段化和复发风险有关的当前SLNB指南.
- 强调长期患者随访的重要性.
主要方法:
- 案例报告的呈现方式.
- 审查当前文献和关于黑色素瘤SLNB的指导方针.
- 临床表现和治疗影响的分析.
主要成果:
- 一名患有原发性侵袭性黑色素瘤和阴性SLNB的患者发生了转移性疾病.
- 转移出现在头部和部区域,呈现出一种"反射"模式.
- 该案挑战了仅基于初始节点状态的假设.
结论:
- 阴性SLNB并不完全排除未来黑色素瘤转移的可能性.
- 高风险黑色素瘤患者需要持续和长期的随访,无论最初的SLNB结果如何.
- 临床警和遵守随访协议对于管理黑色素瘤复发至关重要.
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