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Updated: Jan 9, 2026

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model
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破坏tRNA修饰导致肠道线粒体功能障碍和微生物失调

Di Ran, Yongguo Zhang, Yueqing An

    bioRxiv : the preprint server for biology
    |December 11, 2025
    PubMed
    概括

    该研究显示,减少的Queuine tRNA-ribosyltransferase催化子单元1 (QTRT1) 损害了肠道屏障功能和线粒体健康,影响了肠道微生物群. 恢复线粒体功能可能会提高QTRT1水平以获得治疗效益.

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