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视神经外直径轨迹和临床相关的高内压的儿童的死亡率
Dat Minh-Tan Truong1, Minh Hoang-Nhat Nguyen2, Huy Quang Nguyen3
1Department of Intensive Care Unit, Children's Hospital 2, Ho Chi Minh City 700000, Viet Nam.
World journal of critical care medicine
|December 11, 2025
概括
在入院后48小时内,视神经外直径 (ONSD) 的动态变化在患有高内压 (ICP) 的儿童中预测死亡率. 连续的ONSD超声波测量提供了一个非侵入性的工具,用于早期预后在重症儿科患者.
科学领域:
- 儿科重症监护医学 儿科重症监护医学
- 神经学 神经学
- 医疗成像医学成像
背景情况:
- 光神经外直径 (ONSD) 超声波是一种非侵入性方法,用于检测升高的内压力 (ICP).
- 基线ONSD预测各种神经疾病的成年人死亡率.
- 关于动态ONSD变化及其预后价值的儿科数据有限.
研究的目的:
- 调查在入院后48小时内发生的动态ONSD变化与临床相关性升高ICP的儿童住院死亡率之间的关联.
- 在儿科重症监护中评估串行ONSD测量的预后价值.
主要方法:
- 在越南的高等儿童医院进行前性研究 (2023年11月至2024年8月).
- 住院死亡率是主要结果.
- 在入院时测量了ONSD,在PICU入院后24小时和48小时测量了ONSD.
- 线性混合效应模型分析了ONSD变化和死亡率.
主要成果:
- 分析了69名患有高ICP的儿童;住院死亡率为23.2%.
- 48小时内ONSD动态变化与死亡率增加有显著的相关性.
- 非幸存者在48小时内显示出5.3%的ONSD增加;幸存者显示出5.6%的ONSD减少.
结论:
- 在48小时内进行的连续ONSD超声波测量比基线数据优于预测高ICP的重症儿童的死亡率.
- 这为早期预后提供了一个实用的,非侵入性的工具.
- 动态的ONSD变化为儿科重症监护提供了有价值的预后信息.
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