对视网膜血管瘤进行Palladium-103斑块辐射疗法
Paul T Finger1,2,3, Andrew Lukban2, Ren-Dih Sheu2
1The Department of Ocular Tumor, Orbital Disease and Ophthalmic Radiation Therapy, The New York Eye Cancer Center, New York City, New York, USA.
American journal of ophthalmology case reports
|December 11, 2025
概括
103 (Pd-103) 斑块辐射有效治疗了两个视网膜血管瘤病例,导致瘤回归和视力保存. 这种新的方法为管理这些罕见的血管瘤提供了一个有希望的替代方案.
科学领域:
- 眼科医生 眼科 眼科
- 辐射瘤学 辐射瘤学
- 医学物理 医学物理
背景情况:
- 斑块辐射是治疗眼睛瘤的一种成熟方法.
- 视网膜血管瘤是一种罕见的血管瘤,可以损害视力.
- 之前的治疗方法,如激光光凝血在这些情况下没有成功.
研究的目的:
- 评估-103 (Pd-103) 斑块辐射作为视网膜血管瘤的主要治疗方法的新用途.
- 评估Pd-103支臂疗法对外围视网膜血管瘤的安全性和有效性.
主要方法:
- 两名患有单独的外周视网膜血管瘤的患者接受了Pd-103斑块支臂治疗.
- 对Pd-103,I-125和Y-90进行了比较剂量测量.
- 患者在7天内接受了50和60Gray (Gy) 的顶端剂量.
主要成果:
- 这两种视网膜血管瘤在1年内都显示出大小回归.
- 视网膜排泄物,出血和脱落已经解决.
- 低剂量射入叶 (1.3和1.7 Gy) 表明没有辐射巨病的风险.
结论:
- 在Pd-103斑块支架疗法有效控制瘤生长,并逆转了视网膜血管瘤的排泄.
- 这种治疗可以保持视力,而不会导致辐射巨病或视神经病变.
- Pd-103斑块辐射代表了视网膜血管瘤的可行的初级治疗选择.
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