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MV-Flow成像用于评估妊娠糖尿病的胎盘功能

Jiahao Song¹, Xiaobin Li², Chen Zhu¹

¹Department of Ultrasound, Obstetrics and Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China.

Frontiers in endocrinology

|December 11, 2025

概括

微血管流 (MV-Flow) 成像可以在患有妊娠糖尿病 (GDM) 的女性中可视化胎盘微血管血流. 这种非侵入性技术显示出在GDM怀孕中评估胎盘功能的潜力.

科学领域:

产科和妇科产科和妇科
医疗成像医学成像
血管生物学血管生物学

背景情况:

孕期糖尿病 (GDM) 与母亲和胎儿的血管功能障碍以及不良的围产期结果有关.
通过微血管流成像 (MV-Flow) 评估的微血管指数 (MVI) 提供了微血管功能的非侵入性测量.

研究的目的:

评估传统的多普勒超声波和MV-Flow用于划分胎盘微血管.
探索MV-Flow在GDM怀孕中评估胎盘功能的临床可行性和价值.

主要方法:

包括92名对照组和88名GDM妇女 (怀孕28至36周).
使用传统的多普勒和MV-Flow评估了胎盘微血管.
根据HbA1c水平和分析与新生儿出生体重的相关性,将GDM分层分为子组.

主要成果:

与对照组相比,GDM组的平均MVI显著更高 (P=0.031).
在胎盘MVI和新生儿出生体重之间发现了中等相关性 (r=0.539;P<0.001).
38.95%的最佳MVI值被确定为具有62.9%的敏感性和69.6%的特异性的歧视性GDM.

结论:

MV-Flow 能够可视化和量化 GDM 中的胎盘微血管血流.
MV-Flow显示为评估GDM胎盘功能的一种工具.

关键词:

孕期糖尿病孕期糖尿病微血管流动成像技术微血管流动成像技术胎盘胎盘胎盘胎盘怀孕怀孕怀孕怀孕怀孕超声波超声波是指超声波的使用.

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