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Updated: Jan 9, 2026

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
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Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease

Published on: November 14, 2017

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精神疾病中的多基因分数和环境因素:使用iPSYCH研究的基因环境相互作用分析.

Tahereh Gholipourshahraki1,2, Linda Ejlskov1, Birgitte Dige Semark1

  • 1National Centre for Register-based Research, Department of Public Health, Aarhus University, Aarhus, Denmark.

Research square
|December 11, 2025
PubMed
概括

遗传和环境因素影响精神疾病的风险. 这项研究发现了有限的,适度的基因环境相互作用,强调了需要进行更大规模的研究,以了解复杂的遗传和环境对心理健康的影响.

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Gene-environment Interaction Models to Unmask Susceptibility Mechanisms in Parkinson's Disease

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A Pipeline using Bilateral In Utero Electroporation to Interrogate Genetic Influences on Rodent Behavior06:59

A Pipeline using Bilateral In Utero Electroporation to Interrogate Genetic Influences on Rodent Behavior

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相关概念视频

Gene-Environment Interactions01:20

Gene-Environment Interactions

Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
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Behavioral Genetics and Its Designs01:23

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Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
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Background and Environment Affect Phenotype02:27

Background and Environment Affect Phenotype

Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
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Human Genetics01:28

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Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
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Environmental Influences on Intelligence01:29

Environmental Influences on Intelligence

Despite the strong genetic influence on traits like intelligence, environmental factors significantly shape outcomes. For example, while over 90% of height variation is due to genetic differences, environmental factors such as nutrition also have a notable impact. Similarly, for intelligence, changes in a child's surroundings can significantly alter their IQ. Research shows that enriched environments boost children's academic success and help them develop key cognitive skills. Children...
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Causes of Social Behavior III: Biological and Environmental Influences01:28

Causes of Social Behavior III: Biological and Environmental Influences

Social behavior is a complex phenomenon that arises from the interaction between biological predispositions and environmental influences. This intricate interplay shapes how individuals think, feel, and act in various social contexts. Understanding these mechanisms requires insights from psychology, neuroscience, genetics, and evolutionary theory.Environmental Influences on Social BehaviorEnvironmental factors, including temperature, odors, and visual stimuli, play a crucial role in shaping...
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