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Updated: Jan 9, 2026

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在多民族人群中超越金标准临床模型预测妊娠前的多基因风险评分

Maddalena Ardissino1,2,3,4, Kypros Nicolaides4,5, Frances Conti-Ramsden4

  • 1Medical Research Council, Laboratory of Medical Sciences Imperial College London UK.

Journal of the American Heart Association
|December 11, 2025
PubMed
概括

多基因风险评分 (PRS) 在预测欧洲血统女性的孕前方面提供了适度的改善. 由于在遗传学研究中代表性不足,它们的实用性在非洲祖先的女性中是有限的,这凸显了公平发展的需要.

关键词:
祖先的血统 祖先的祖先基因组学就是基因组学.多基因分数的多基因分数.孕前症是什么意思怀孕 怀孕 怀孕 怀孕 怀孕风险预测风险预测

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