使用99DOTS (直接观察治疗,短疗程) 应用程序改善纳米比亚结核病治疗的坚持:混合方法研究
M Claassens1, P Steenkamp2, R Gavioli2
1Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa; Department of Human, Translational and Biological Medical Sciences, School of Medicine, University of Namibia.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde
|December 11, 2025
概括
99DOTS计划改善了纳米比亚移动土著人口对结核病治疗的坚持. 这种创新的方法,整合了直接观察的治疗,短时间的过程,显示出对高负荷设置的希望.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 医疗卫生技术 技术 技术
背景情况:
- 基于社区的直接观察结核病 (TB) 治疗 (C-DOT) 对于纳米比亚的移动土著人口来说是具有挑战性的,因为结核病的发病率很高,坚持治疗的程度很低.
- 现有的C-DOT模型不适合游牧群体,需要创新的解决方案.
研究的目的:
- 在纳米比亚的 Tsumkwe 试点实施 99DOTS (直接观察治疗,短程) 计划,以提高移动土著人民的结核病治疗坚持.
- 在C-DOT框架内评估99DOTS应用程序的可行性,可访问性和用户体验.
主要方法:
- 99DOTS计划的试点研究从2019年第二季度到2020年第一季度进行.
- 与20名患者和2名医疗保健工作者进行了半结构面试,以评估治疗完成和计划经验.
- 程序服务器数据被用来监测治疗坚持.
主要成果:
- 大多数接受采访的患者报告说,家庭和卫生系统提供支持,卫生保健工作者定期对患者进行随访.
- 发现99DOTS应用程序是用户友好和可接受的,参与者愿意公开使用它.
- 虽然只有6名受访者完全遵守药物,但错过的剂量相对较少,这表明有改善的潜力.
结论:
- 99DOTS计划是一个可行的,创新的,可访问的工具,用于提高结核病治疗的坚持.
- 将99DOTS集成到现有的C-DOT方法中可以改善高负载环境中的结果.
- 国家结核病计划应该考虑在类似人群中采用99DOTS,以提高治疗坚持.
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