根据组织学亚型的子宫体癌的全球趋势和差异:基于人口的分析分析
Quan Zhou1,2, Yan Guo3, Shuo Chen1,2
1Department of Obstetrics and Gynecology, Shengli Clinical Medical College, Fujian Medical University, Fujian Provincial Hospital, Fuzhou, Fujian, China.
International journal of surgery (London, England)
|December 11, 2025
概括
子宫体癌 (UCC) 的发病率根据亚型在全球范围内有所不同,亚洲的侵袭性类型增加,其他地区的发病率稳定. 发育水平影响诊断和亚型分布,需要定制的预防策略.
科学领域:
- 流行病学 流行病学
- 在瘤学瘤学.
- 全球健康 全球健康
背景情况:
- 子宫体癌 (UCC) 的发病率显示出全球差异,其中具有侵略性的亚型导致死亡率.
- 了解UCC亚型的地理和时间趋势,特别是在低收入和中等收入国家 (LMICs),是有限的.
研究的目的:
- 通过组织学亚型分析全球UCC发病率模式.
- 调查UCC亚型的时间趋势和地理变化.
- 检查社会经济因素和年龄对UCC亚型分布的影响.
主要方法:
- 在五大洲利用的癌症发病率 (CI5) 数据 (1988-2017) 来自65个国家.
- 计算UCC亚型的年龄标准化发病率 (ASR).
- 用于时间趋势分析和区域模式的地理空间映射的员工结合点回归.
主要成果:
- 观察到不同的地理模式:东欧的下降率,亚洲的上升率.
- 确定了社会经济梯度:社会人口统计指数 (SDI) 高的国家显示更多的腺癌,而SDI 低的地区有更多的未指定的类型.
- 已注意到特定年龄的分布在65-69岁达到顶峰,老年人群的未指定的比例更高.
结论:
- UCC流行病学由亚型演变,受国家发展水平和诊断能力的影响.
- 迫切需要亚型特定的预防和增强的病理基础设施,以减少全球UCC差异.
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