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Updated: Jan 8, 2026

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由PIAS1进行EBNA1 SUMOylation抑制了EBV的溶性复制,并增强了插曲维护

Febri Gunawan Sugiokto1,2,3, Kun Zhang4, Yunash Maharjan1,2,3

  • 1Program in Microbiology and Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

mBio
|December 11, 2025
PubMed
概括

SUMO E3酶PIAS1通过SUMOylation调节爱斯坦-巴尔病毒核抗原1 (EBNA1) 的功能. 这一过程对于维持病毒发作和抑制EBV重新激活至关重要,从而影响病毒的持续性.

关键词:
在EBNA1中,EBNA1是指EBNA1.爱斯坦-巴尔病毒病毒.在 PIAS1 的基础上.这就是SUMOylation的作用.一个剧集的情节.延迟时间 延迟时间质粒复制 (oriP) 的起源

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