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Updated: Jan 8, 2026

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基于纳米材料的治疗策略来修复脊髓损伤:利用多功能来克服病理生理学挑战

Taile Cheng1,2,3, Youde Cao1,2,3, Bing Liang1,2,3

  • 1Department of Pathology, College of Basic Medicine, Chongqing Medical, University, 1 Yixueyuan Road, Yuzhong District, Chongqing 400016, P. R. China. 420306100@qq.com.

Biomaterials science
|December 11, 2025
PubMed
概括

纳米材料通过向神经炎症和促进神经再生,为脊髓损伤 (SCI) 提供了新的希望. 这些先进材料为中枢神经系统损伤后的愈合和功能恢复创造了更好的环境.

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In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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