以前接受放射治疗的癌症患者的辐射回忆性皮肤炎:范围审查
Paloma Gomes1, Amanda Gomes de Menêses2, Renata Cristina de Campos Pereira Silveira3
1Faculty of Health Sciences. Interdisciplinary Research Laboratory Applied to Clinical Practice in Oncology - LIONCO, University of Brasília, Campus Darcy Ribeiro, Asa Norte, Brasília, DF, 70910-900, Brazil.
概括
辐射回忆性皮肤炎 (RRD) 是癌症患者的一个显著不良事件,通常与多塞塔塞尔等化疗剂有关. 像COVID-19感染和疫苗接种这样的新触发因素正在出现,需要进一步的研究以更好地管理.
科学领域:
- 在瘤学瘤学.
- 皮肤病学 皮肤病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 辐射回忆性皮肤炎 (RRD) 是放射治疗后发生的不良皮肤反应.
- 它可以表现为急性或慢性,影响正在接受癌症治疗的患者.
研究的目的:
- 综合地绘制有关先前接受放射治疗的癌症患者辐射回忆性皮肤炎 (RRD) 的现有证据.
- 确定与RRD相关的模式,触发因素和临床特征.
主要方法:
- 按照JBI协作指南进行了系统范围审查.
- 在多个数据库 (PubMed,CINAHL,LILACS,Scopus,Web of Science,Cochrane) 和灰色文献中进行了广泛的文献搜索.
- 包括的研究发表在任何语言,没有出版年限.
主要成果:
- 该审查综合了来自210项研究的数据,主要是病例报告和系列 (84.7%).
- 乳腺癌患者约占RRD病例的48%.
- 化疗,特别是多塞 (13.5%),是最常见的触发因素 (73.6%),放射治疗剂量从8到65Gray.
- 症状包括红斑,脱皮,,,,疼痛,,死亡和出血.
结论:
- 辐射回忆性皮肤炎 (RRD) 是一个值得注意的不良事件,特别是在乳腺癌患者中,经常与多塞塔克塞尔和多克索鲁比辛化疗相关.
- 新出现的RRD触发因素包括COVID-19感染和接种疫苗.
- 对RRD机制和治疗策略的进一步调查对于患者护理至关重要.
相关概念视频
Skin Cancer
5.7K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.7K
Radiation: Applications
1.7K
The average temperature of Earth is the subject of much current discussion. Earth is in radiative contact with both the Sun and dark space; it receives almost all its energy from the radiation of the Sun and reflects some of it into outer space. Dark space is very cold, about 3 K, so Earth radiates energy into it. For instance, heat transfer occurs from soil and grasses, the rate of which can be so rapid that frost can occur on clear summer evenings, even in warm latitudes.
The average...
The average...
1.7K
Biological Effects of Radiation
17.5K
All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...
17.5K
Radiological Investigation III: Pulmonary Angiogram and PET Scan
374
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
374


