乌干达抗生素耐药性的社会经济负担:疾病的成本研究
Elly Nuwamanya1,2, Jonathan Mayito3, Stephen Okoboi3
1Infectious Diseases Institute, College of Health Sciences, Makerere University, P.O Box 22418, Kampala, Uganda. enuwamanya@idi.co.ug.
PharmacoEconomics - open
|December 11, 2025
概括
抗生素耐药性 (ABR) 每年使乌干达损失143万美元,生产力损失是最大的因素. 该研究强调了ABR的重大经济影响,特别是对女性的影响,并呼吁采取基于性别的干预措施.
科学领域:
- 公共卫生 公共卫生
- 卫生经济学 卫生经济学
- 传染性疾病 传染性疾病
背景情况:
- 抗生素耐药性 (ABR) 是一个日益增长的全球威胁,由于不适当的处方和滥用.
- ABR导致长时间住院和增加死亡率,影响医疗保健系统和经济.
- 这项研究量化了ABR在乌干达地区转诊医院的经济负担.
研究的目的:
- 为了估计抗生素耐药性 (ABR) 在乌干达九家区域转诊医院 (RRHs) 的社会经济负担.
- 分析这种经济负担的组成部分,包括直接的医疗保健成本,患者成本和生产力损失.
- 确定ABR经济影响中的潜在基于性别的差异.
主要方法:
- 从社会角度进行了基于患病率的疾病成本研究.
- 使用自上而下的微成本计算方法来确定直接的医疗保健成本.
- 用临床数据和人力资本方法估计了患者成本和生产率损失.
主要成果:
- 九个RRH的ABR的年度社会成本估计为143万美元 (乌干达GDP的0.003%).
- 损失的生产力占总成本的82%,其次是非正式护理 (10%) 和直接医疗保健成本 (8%).
- 与男性相比,女性的社会成本和每个患者的成本显著高于男性.
结论:
- 抗生素耐药性给社会带来了巨大的经济负担,需要紧急干预.
- 针对性,基于性别的干预措施对于减轻ABR不断升级的经济影响至关重要.
- 这些发现可以为未来对ABR缓解策略和抗微生物药物管理政策的经济评估提供信息.
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